Polypeptide hormone secreted by the alpha-cells of the pancreas. Supra-physiological doses have previously been advocated in the management of beta-blocker and calcium channel blocker poisoning but this practice is now largely abandoned. Please see our glucose page for the latest evidence and best practise.
Chris Nickson talks us through the history of glucagon and whether it is effective:
References
- Bailey B. Glucagon in beta-blocker and calcium channel blocker overdoses: a systematic review. Journal of Toxicology – Clinical Toxicology 2003; 41(5):595-602