Do we, as a global medical profession, truly know whether or not tPA is a beneficial treatment early on in the presentation of a CVA?
Schrödinger’s Fence…or, where we currently sit on the matter of thrombolysis in Acute Stroke. An Opinion Piece on IST-3
Short editorial snippets from Vol. 24 Issue 5 of Emergency Medicine Australasia (EMA Journal) published online on 9 October 2012.
A nicely written comment on IST-3 which is similar in conclusion to my original post (i.e. this is a rubbish study that adds nothing and contains badly orchestrated smoke and mirrors, but there probably is a group who will benefit, we just don’t know exactly who they are yet, and future research shouldn’t cast the […]
The illustrious David Newman of smartem.org and thennt.com speaks, and agrees with me. IST-3 is a debacle! “With advances in scientific literacy it has been years since I have seen a top journal allow authors to proclaim a conclusion in direct conflict with their own primary study results. And yet the authors blithely conclude that thrombolytics […]
So IST-3 is out… You can register with the Lancet for free and get a copy here. You really need to read it in full. To me the abstract appears barely related to the full text. Don’t take my word for it though. Read it before you read on!!! IST-3 seemed poised to answer the […]