Cerebellar disease

Overview

• Important causes of diseases affecting the cerebellum

Causes

Midline

• Paraneoplastic syndrome
• Midline tumour

Unilateral

“MVPS”

• SOL – Tumour, abscess, granuloma
• Vascular – ischaemia / infarction, haemorrhage
• Paraneoplastic syndrome
• Multiple sclerosis

Bilateral

• Drugs & toxins – e.g. phenytoin, alcohol (No1), Lithium
• Friedrich’s ataxia
• Hypothyroidism
• Paraneoplastic syndrome
• Multiple sclerosis
• Trauma (punch drunk)
• Arnold Chiari malformation
• Large SOL – causing cerebellar pressure