Injections are most commonly administered IM (intramuscular) or SC (subcutaneously)
Route of administration for small volumes (0.5–1.0mL) of water-soluble medication into the loose connective tissue beneath the dermis. Absorption is slow, but usually complete in patients without circulatory compromise. Onset of action is delayed (up to 30–45 minutes).
- Circulatory shock
- Reduced local tissue perfusion
- Very thin patients (may have inadequate adipose tissue for subcutaneous injection)
- Bleeding diathesis
- Local tissue irritation, inflammation, erythema or pain.
- Sterile abscess (collection of medication within the skin and appears as a hard painful lump).