We recently wrote about the amplification of food anaphylaxis in Australia, where the rate of fatalities has increased 3-fold in the last 15 years. Smith and colleagues (Gold Coast, Australia and New York) have just published a paper reviewing the epidemiology, in-vitro and in-vivo studies and hypothesize a “false alarmin” method via which food allergies may develop … [Read more...] about Food allergy amplification all the RAGE
Anaphylaxis is increasingly common. The patient population death rate for anaphylaxis is Australia in 2013 was over double that reported in the UK Dr Ray Mullins, an allergist in Canberra, and colleagues from Sydney and Singapore have recently reported an increase in in the number of anaphylaxis fatalities in Australia. This is currently trending towards a 3 fold increase in … [Read more...] about Australian Anaphylaxis Amplification
The placebo effect is well-known in modern medicine. Unfortunately, the most effective medicines we’ve ever discovered are more often used as placebos rather than cures. What are these medicines? Antibiotics. They’ve added 20 years to the average human life expectancy, some would call this a “miracle”. In-fact “preserve the miracle” is the official slogan for Antibiotic … [Read more...] about Antibiotics: Preserve the miracle?
The world of urticarial pathophysiology and dermal manifestations of allergy and urticaria has always fascinated me - although I have found that clinically defining some of the finer sub-divisions allergic and non-allergic urticarias can be a little taxing (see causes mnemonic FIT MID CHIMP) To add more confusion to the mix, I thought I might introduce some images from … [Read more...] about Palmaris slapus abdominus
Dealing with a patient suffering from acute anaphylaxis attack can be a frightening and challenging experience for even the most seasoned emergency clinician. The following 10 pearls and pitfalls on management of anaphylaxis was taken from an editorial published in the Southern Medical Journal by Dr Richard D deShazo. This short brilliant article gives you the Top 10 things … [Read more...] about Pearls and Pitfalls in Anaphylaxis