- Pericardial effusion
- While percussing the posterior chest, dullness at the left lower lung field is Ewart’s sign of pericardial effusion, while right-sided dullness is Conner’s sign. Disappearance of Ewart’s or Conner’s signs when the patient sits up and leans forward is Bamberger’s sign of pericardial effusion. [Reference]
- Bertolotti’s syndrome
- It is an atypical cause of low back pain or buttock pain caused by a transitional lumbar vertebrae with a large, “spatulated” transverse process that either fuses with the sacrum (sacral ala) or ilium, or forms a pseudo-articulation at that location (Seen on a lumbar spine AP X-ray).
- This is a congenital abnormality, but doesn’t usually become symptomatic until a patient’s 20’s or 30’s. [Reference]
- One of the most demonised patients in history – Gaetan Dugas – for spreading HIV to the US
- Initially, however, the CDC researcher, who was studying cases in Los Angeles, California, referred to Dugas not as “patient zero”, but as “patient O”, the letter “O” standing for “outside California” and subsequently the term “patient zero” was born.
- In 2016 Nature published a report from Dr. Michael Worobey’s team who conducted a genetic study that looked at blood samples taken from gay and bisexual men in 1978 and 1979 as part of a hepatitis B study, and based on the results of the data, concluded that Dugas was not the source of the virus in the U.S. “On the family tree of the virus, Dugas fell in the middle, not at the beginning.” [Reference]
- Akathisia – a syndrome characterized by an inability to remain seated, with motor restlessness and a feeling of muscular quivering; may appear as a side effect of antipsychotic and neuroleptic medication.
- Hawkinsinuria, also called 4-Alpha-hydroxyphenylpyruvate hydroxylase deficiency, is an autosomal dominant metabolic disorder affecting the metabolism of tyrosine.
- Patients present with metabolic acidosis during the first year of life, which should be treated by a phenylalanine- and tyrosine-restricted diet. The tolerance toward these amino acids normalizes as the patients get older. Then only a chlorine-like smell of the urine indicates the presence of the condition, patients have a normal life and do not require treatment or a special diet. [Reference]