CLASS
- anti-arrhythmic
MECHANISM OF ACTION
- low doses = non-selective beta receptor antagonist
- high doses = prolongs action potential
PHARMACEUTICS
- oral tablet
DOSE
- 240-320mg bd
INDICATIONS
- SVT
- VF
- AF
ADVERSE EFFECTS
- prolongation of QT interval
- torsades de pointes
- decreased myocardial contractility
- bradycardia
- bronchospasm (not recommended in asthma)
PHARMACOKINETICS
- Absorption –
- Distribution – no protein binding
- Metabolism – no metabolism
- Elimination – renal
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