March 12, 2010

Pulmonary Puzzle #004

Consider a 56 year old male with no past medical history presenting with 10 days of fevers, chills, myalgias and cough followed by worsening breathlessness over the past 4 days.  His admission chest X-ray is shown below:

image 18 Pulmonary Puzzle #004

Questions

Q1.  Describe the chest X-ray findings:

The chest X-ray demonstrates a dense alveolar infiltrate involving the lateral aspect of the left mid-zone.

The patient rapidly deteriorated with fulminant shock, multiorgan failure and worsening oxygenation.  The following chest ray is taken shortly after ICU admission

image 26 Pulmonary Puzzle #004

Q2. What devices are present on the chest X-ray?

  1. right IJ central line
  2. left IJ vascath (dialysis catheter)
  3. nasogastric tube
  4. endotracheal tube

Q3.  Which device is in the wrong place and where should it be?

The left IJ vascath is in too far.  Central lines and vascaths should not be inserted beyond the superior extent of the pericardial reflection (which corresponds to the take off of the right main bronchus) because beyond this point they can erode through the superior vena cava or the right atrium / ventricle leading to pericardial tamponade and death

A subsequent chest X-ray is as follows:

 Pulmonary Puzzle #004

Q4. What has happened since the previous chest x-ray?

A chest drain has been inserted draining the left pleural effusion and the vascath has been pulled back to an appropriate position.

The following microbiology is obtained:

Microbiology SpecimenDescription
Respiratory SputumLiquid, blood stained
Moderate growth of normal URT flora
Heavy growth of Streptococcus pyogenes
Blood CultureSpecimen: Venous
Growth of Gram positive cocci resembling streptococci in aerobic bottle after 1 day.
Isolate identified as Streptococcus pyogenes

Q5.  What is the diagnosis?

The overwhelming evidence here points to a diagnosis of S. pyogenes pneumonia, bacteraemia and empyema!  The clinical history suggests the possibility of a bacterial infection complicating influenza and, indeed, this turned out to be the case:

 Pulmonary Puzzle #004

Influenza may predispose to invasive group A Strep disease (at least it does in mice)

Q6.  What is the prognosis?

In a series of 2079 cases .of invasive group A Strep infection, the case fatality rate was 38% for pneumonia, compared with 26% for patients with necrotizing fasciitis.

Pulmonary Puzzle #003

Consider a 73 year-old female admitted with vomiting and subsequent chest pain.
This is her erect AP admission chest X-ray.

Pulmonary Puzzle #003

Pulmonary Puzzle #003

Questions

Q1. Describe the chest X-ray?

There is extensive mediastinal emphysema and bilateral pleural effusions.

Q2. What is the diagnosis?

Boerhaave syndrome or so-called ’spontaneous’ rupture of the oesophagus. Often it is not really spontaneous as it occurs with vomiting.

Herman Boerhaave described the condition in 1724, in a classic example of clinicopathological correlation, when faced with the case of the Grand Admiral of the Dutch Fleet, a roast duck and three litres of juniper beer…

Legend has it that letters Boerhaave received bore no address and were simply mailed “To the Greatest Physician in the World”.
- from Tan SY, Hu M. Hermann Boerhaave (1668-1738): 18th century teacher extraordinaire. Singapore Med J. 2004 Jan;45(1):3-5. PMID: 14976574

Q3. What is the classic presentation of this condition?

“A middle-aged man presenting with sudden-onset severe chest or epigastric pain, often radiating to the back or shoulder, after repeated episodes of retching or vomiting in association with over-indulgence in food and alcohol.”
Most presentations of Boerharve’s syndrome are atypical and the diagnosis often requires a high index of suspicion – usually an “oesophogram” of some sort is required.
In about 1 in 4 cases there is no history of vomiting!

Q4. What is the Mackler triad?

The Mackler triad consists of:

  1. vomiting
  2. lower thoracic pain
  3. subcutaneous emphysema

Although it supposedly defines the classic features of Boerhaarve’s syndrome it is probably not worth knowing because it is rarely found and is of negligible clinical utility in the real world.

Q5. Outline the management of this condition.

This a a highly lethal condition – it is essentially 100% fatal if left untreated. Overall mortality is about 30%.

The cornerstones of management are:

  • aggressive resuscitation
  • early surgical intervention
  • broad-spectrum antibiotics

Resuscitation should be followed by prompt surgical intervention (call the thoracic surgeons!). The time between onset of symptoms and surgery is the greatest predictor of patient survival.

  • best outcomes if surgery is performed <12 hours from onset.
  • mortality probably increases to ~50% at 24 hours, and to ~90% at 48 hours.

Empirical antibiotics are indicated and should be broad spectrum to cover gram positives (including enterococcus), gram negatives and anaerobes. Some also advocate antifungal cover with fluconazole in initial empirical treatment as Candida is commonly grown from drain fluid in these patients (sometimes I give this and sometimes I don’t and I’m not sure whether doing this is a good idea or not).

Conservative management (i.e. without surgery) may be appropriate in some situations:

  • presentation >48 hours
  • debilitated premorbid condition
  • a contained rupture, with minimal symptoms and negligible clinical evidence of sepsis.

Although there is little consensus for the management of this rare condition, one suggested treatment algorithm is:

boerhaarves mgt Pulmonary Puzzle #003

Quiz Radiology 023

An 18 year old woman with a history of asthma since childhood presents with a one month history of weight loss, cough and malaise. She has been treated with two courses of antibiotics by her local GP. She now presents with increasing shortness of breath. A CXR is shown.

Question

a. Describe the X-ray. (50%)
b. List your differential diagnosis. (50%)

20031 8 CXR 590x635 Quiz Radiology 023

Answer

FACEM VAQ Exam 2003.1 – Question 8

  • Overall pass rate for this question was 65 / 83 (78.3%).
  • This question also posed problems with image quality which made answering and marking difficult for candidates and examiners alike.
  • Examiners noted that answers rarely had a systematic approach for describing the X-ray and for listing causes of fluid in the pleural space.

Quiz Radiology 019

A distressed 60 year old man from a nursing home is brought into the ED having ‘choked on his dentures’.

Question

a. Describe the CXR findings. (50%)
b. What further investigations may be indicated in this man? (50%)

20032 4 CXR 590x484 Quiz Radiology 019

Answer

FACEM VAQ Exam 2003.2 – Question 4

  • Overall pass rate for this question was 57 / 82 (69.5%)
  • A CXR showing dentures overlying the mediastinum with probable air in the neck soft tissues.
  • The examiners felt that this was an extremely good question that tested candidates’ diagnostic ability, perception, common sense and knowledge.
  • Nevertheless it could be passed largely by considering the possibility of oesophageal perforation due to a foreign body.
  • Common errors included not considering oesophageal perforation, indicating tracheal perforation more likely, thinking the denture wires to be sternotomy wires, use of barium in diagnostic studies and failure to include a preoperative workup in investigations.

Quiz Paediatrics 014

A two month old baby girl has been intubated for respiratory distress and drowsiness. The PaO2 is 82% post intubation.

Question

a. Describe and interpret the CXR findings. (50%)
b. List the steps you would take to improve this infant’s poor arterial O2 saturation. (50%)

Right Main Bronchus Intubation

Answer

FACEM VAQ Exam 2004.1 – Question 6

  • Overall pass rate for this question was 57 / 69 (82.6%).
  • A CXR demonstrating a right main intubation is shown.
  • Examiners expected that the right main bronchus intubation would be recognized and were surprised that some candidates interpreted the xray as showing a pneumothorax.
  • The question was an opportunity for candidates to demonstrate practical paediatric resuscitation knowledge.
  • It was expected that the answer in b) would include resorting to BVM with an Fi02 of 1.0 while other steps were being taken to improve oxygenation.

Quiz Paediatrics 009

An 11 year old female with Down’s syndrome presents with acute respiratory distress following a 3 day history of fever, rhinorrhoea and dry cough. A CXR is performed following her intubation.

Question

a. Describe and interpret her CXR. (100%)

20061 5 CXR Quiz Paediatrics 009

Answer

FACEM VAQ Exam 2006.1 – Question 5

  • The overall pass rate for this question was 35/40 (87.5%).
  • The CXR given shows extensive, bilateral pulmonary infiltrates
  • It was expected that the candidates would be able to describe the CXR accurately and demonstrate that they are able to interpret the CXR in a systematic way, noting major positives and negatives,and including lung fields, cardiac size and borders, bone, diaphragms etc.
  • It was also expected that the candidate could interpret the CXR sensibly in the clinical context (Down’s syndrome, dry cough) that was given, form a reasonable differential diagnosis, recognizing that the most likely diagnosis was infection, types of infection likely (both typical and atypical organisms), with other possibilities less likely.

Quiz Radiology 009

A 52 year old woman presents to your emergency department with gradually increasing breathlessness over the preceding three days. It is one week since her last chemotherapy treatment for cancer.

His observations are:

BP 130/70 mmHg supine
RR 28 /min
Temp 36.5 Celcius
02 90 %RA

Question

a. Describe her Chest X-ray. (50%)
b. Outline your differential diagnoses (50%)

20071 6 CXR O s Quiz Radiology 009

Answer

FACEM VAQ Exam 2007.1 – Question 6

  • Overall pass rate for this question was 39/55 (70.9%).
  • X-ray showed a large left pleural effusion, multiple discrete lung parenchymal lesions typical of metastatic lung disease and a portocath.
  • This was a high discrimination question in the opinion of the examiners.
  • Good responses provided a good description of the radiograph and a reasoned discussion of the possible diagnoses.
  • Candidates failed because of poor use of x-ray descriptives, lack of a systematic technique and vague/ inadequate differentials.

Quiz Radiology 008

A 20 year old man presents to your emergency department with central chest pain that commenced after recreational drug use at a party two hours earlier.
His observations are:

HR 108 /min
HR 150/85 mmHg supine
SO2 98 %

Question

a. Describe and interpret his Chest X-ray (50%)
b. Outline your management. (50%)

20072 2 CXR O s Quiz Radiology 008

Answer

FACEM VAQ Exam 2007.2 – Question 2

  • The overall pass rate for this question was 38/77 (49.4%).
  • Chest X-ray showed mediastinal and subcutaneous emphysema.
  • The examiners felt that this was an easy question poorly answered by many candidates.
  • Satisfactory answers systematically described the image and interpreted it in the light of the clinical scenario. Management required knowledge of the supportive care of this condition and safe disposition of a drug affected patient.
  • Unsatisfactory answers failed to address the above or suggested the inappropriate insertion of an intercostal catheter.

Quiz Radiology 006

An 80 year old male pedestrian is brought to your emergency department 30 minutes after being struck by a motorcycle at high speed.

Question

Describe and interpret his Chest X-ray (100%)

20081 2 CXR O s Quiz Radiology 006

Answer

FACEM VAQ Exam 2008.1 – Question 2

  • Chest X-ray of trauma patient showing multiple rib fractures and underlying area of pulmonary contusion or haemothorax.
  • The overall pass rate for this question was 34/62 (54.8%).
  • Good answers showed a systematic approach to reading an X-ray, identified the key abnormalities, commented on relevant negatives and suggested the possibility of a flail segment.
  • Poor answers missed major findings or showed lack of a systematic approach.

Radiological Oddity #012

Picture7