Funtabulously Frivolous Friday Five 033

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Yay…it’s Friday. Time to challenge that cerebral cortex and put on those ‘mental’ dancing shoes as we trip the light fantastic of medical trivia, and lift the latch on the cage of the tiger of tease…so fasten your brastraps in anticipation of the Funtabulously, Frivolous Friday Five…

Citalopram overdose

Nomogram for assessment of pro-arrhythmic risk in drug-induced QT prolongation

aka Toxicology Conundrum 017 Your next patient is a 26 year-old female who claims to have ingested 40 x citalopram hydrobromide tablets (40mg each) about 3 hours ago. She appears anxious with a heart rate of 95/min. She is alert, orientated and has bilaterally equal 4mm pupils. Further examination is unremarkable. Questions Describe the toxicodynamics [...]