Unusual Urine 005
What is the biochemical cause of purple urine?
Urine can present in a veritable rainbow of colours…
- Purple discoloration can occur in alkaline urine as a result of the degradation of indoxyl sulfate (indican), a metabolite of dietary tryptophan, into indigo (which is blue) and indirubin (which is red)
- Bacteria such as Providencia stuartii, Klebsiella pneumoniae, P. aeruginosa, Escherichia coli, and enterococcus species are most commonly implicated
- The clinical course is benign, and the urine typically clears with resolution of the bacteriuria and acidification of the urine.