aka Oncology Quandary 004
45 year old woman with metastatic ovarian cancer is admitted for VATS pleurodesis (video-assisted thoracoscopic surgery) and drainage of bilateral pleural effusions. Her admission chest X-ray is shown below:
During her operation, 2L of fluid is drained from the left chest. Shortly thereafter, pink frothy sputum starts coming out of the ET tube and the patient markedly desaturates.
The patient is transferred to the intensive care unit and the following chest x-ray is obtained:
Q1. Describe the chest X-ray.
There is an ET tube, a right IJ central line and bilateral chest drains in situ. There is also ECG monitoring on the patient. Most importantly:
There is near white-out of the left hemi-thorax.
Q2. What is the likely diagnosis?
The history and chest X-ray appearances suggest that the likely diagnosis:
re-expansion pulmonary oedema
Q3. What are the risk factors for this condition developing?
Risk factors include:
- long-standing collapse of the lung prior to aspiration
- drainage of a large amount of fluid or air over a short period of time
- application of suction
Q4. What is Meig’s syndrome?
Meig’s syndrome is the triad of:
- pleural effusion and
- benign ovarian tumor (fibroma)
It resolves after the resection of the tumor. For reasons unknown, the pleural effusion is classically on the right side. This patient has metastatic ovarian cancer with associated pleural effusion so this is not it!
Joe Vincent Meigs, was an American obstetrician and gynaecologist. Meigs was a grandson of Captain Joe Vincent Meigs, who invented an experimental steam monorail known as the Meigs single-track elevated railroad.