Melioidosis – Lab without walls

Meliodosis-Petri

Melioidosis is a fascinating disease, with a distinct geography, a wide range of clinical presentations and a complex pathogenesis.

Superbugs in the News

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In case you missed it, ABC’s 4 Corners ran a story on multi-resistant organisms.

Losing the War on Resistant Gram Negatives

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Extended spectrum beta-lactamases (ESBLs) have been a challenge to antimicrobial therapy since the 1980s and still continue to be…

The perfect human pathogen?

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With winter comes norovirus. This Q&A post tests your knowledge of what may be the perfect human pathogen.

The Bordetella pertussis epidemic

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Could antigenic changes to P.69 Prn but not PTX explain the phenomenon of colonisation and attenuated disease in some vaccinated cases?

Malaria vaccine

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The malaria disease is caused by a Plasmodium protozoal parasite, post proboscis penetration by an infected Anopheles mosquito. Here we discuss Malaria vaccine

A New Threat Tied in to Intensive Care

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Environmental selection pressures are a driving force in the adaptive processes driving adaptive processes in organisms.

The Four R Rule

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It would be fascinating to run a fly-on-the-wall documentary on life at trolley level in a local Emergency Department. When you’ve been there, done it and survived to watch TV again, the dramatised version served up in your average medical soap is about as true to life as Harry Potter. Someone will just have to come up with ED-trolleycam. The MicroGnome was left under no illusions when struck down with a travel-related infection following a week with the Lab Without Walls in East Timor. He became a victim of the Four R Rule:

Adaptive parasitology and free parking

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Natural Killer Not Functioning to Combat Non-Presentation of MHC Due to Downstream Malfunction of Toll Like Receptor. A lesson in adaptive parasitology, and free parking. Full publication review from the Journal of Life as a Poor Science Analogy.

EBM Meningitis

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EBM review of the assessment and management of meningitis and Meningococcaemia