Funtabulously Frivolous Friday Five 034

Yay…it’s Friday.
Time to challenge that cerebral cortex and put on those ‘mental’ dancing shoes as we trip the light fantastic of medical trivia, and lift the latch on the cage of the tiger of tease…so fasten your brastraps in anticipation of the Funtabulously, Frivolous Friday Five…and try not to think too much!

Question 1

  • What condition present with Gottren’s papules, heliotrope rash and the shawl sign?

shawl sign

Gottren's papules

Question 2

  • With which condition is Felty’s syndrome associated?

  • Rheumatoid arthritis
  • Is a condition that is associated with seropositive (rheumatoid factor [RF]–positive) rheumatoid arthritis.
  • It is characterized by the triad of RA, splenomegaly, and neutropenia.
  • This condition was first described by A.R. Felty as reported in 1924: Chronic arthritis in the adult, associated with splenomegaly and leucopenia. A report of 5 cases of an unusual clinical syndrome. Bulletin of the Johns Hopkins Hospital, Baltimore, 1924, 35: 16. [Reference]

Question 3

  • The bulb of meadow saffron yields which chemotherapeutic agent?

  • Colchicine.
  • The correct name for the plan is Colchicum autumnale.

Colchicum autumnale

Question 4

  • What was Devonshire colic?

  • Lead poisoning from cider.
  • Devonshire Colic is an affliction caused by lead poisoning that affected the people of Devonshire, England throughout the 17th and 18th centuries.
  • The infirmity was the result of the use of lead in the production of the apple cider as the press was constructed in part by lead. This discovery was made by Dr. George Baker in the 1760s and by the mid 1820s lead poisoning due to cider was nearly non existent.
  • The first written account comes from 1655. Symptoms began with severe abdominal pains and the condition was occasionally fatal. Cider is the traditional drink of Devonians, and the connection between the colic and apple juice and cider drinking had been observed for many years. This was commonly attributed to the acidity of the beverage.
  • William Musgrave’s publication De arthritide symptomatica (2nd edn, 1715) included the first scientific description of ‘Devonshire colic’

Question 5

  • In 1932, Gustav Von Bergmann demonstrated an unusual effect by distending the lower oesophagus of the dog. What was it?

  • Coronary artery constriction.
  • Von Bergmann was a proponent of “functional pathology”, and is considered to be one of the founders of psychosomatic medicine.
  • His research involved investigations into gastro-intestinal ulcers, hypertension and studies of the autonomic nervous system.
  • Today, the “Gustav-von-Bergmann-Medaille” is the highest honor awarded by the Deutschen Gesellschaft für Innere Medizin(German Society of Internal Medicine).

…and remember kids

…a sick note is not always the best idea…!

Too drunk to work

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