Lumbar Puncture

Lumbar puncture is a potentially uncomfortable procedure that must not be rushed. It is essential to position the patient correctly and take your time.

Lumbar Puncture Reference Links

Indications

  • Diagnostic
    • Evaluate CSF in suspected meningitis, SAH, carcinomatosis, multiple sclerosis and syndromes such as Guillain-Barré.
    • Measure CSF pressure.
  • Therapeutic
    • Intrathecal administration of medications.
    • Removal of CSF in benign intracranial hypertension.
  • Indications for CT head scan prior to LP
    • Age >60 years
    • Immunocompromised state
    • Neurological findings, such as ALOC or focal neurological deficits
    • Objective evidence of raised ICP such as papilloedema, bradycardia and headache
    • History of CNS lesion (e.g. stroke, mass lesion, focal CNS infection)
    • Seizure activity in the preceding week

Complications

  • Failure to obtain adequate CSF
  • Post-LP headache
    • Increased risk with large bore needle, multiple attempts, excessive CSF removal, dehydration, women
    • Reduce risk by using an atraumatic needle (e.g. Sprotte or Whitacre) rather than a cutting needle (e.g. Quincke) – (separation rather than cutting of dural fibers) and by orienting the bevel of the needle parellal to the long axis of the spine (back flexion is more likely to close a longitudinal rather than a horizontal slit.
  • Brain-stem compression secondary to brain herniation
  • Local haemorrhage and epidural haematoma
  • Back pain (very common)
  • Infection (very rare): epidural abscess, meningitis
  • Acquired intraspinal epidermoid tumors (due to use of an LP needle without a stylet)

Handy Hints

  • Positioning:
    • Prone positioning may reduce risk of post-LP headache [Reference: Medscape]
    • Failure of postural manoeuvres to prevent lumbar puncture headache Hilton Jones – 1982 PDF
    • Flexion of the neck may be uncomfortable and is not necessary
  • Sitting position for LP
    • When performing LP sitting the legs should not be hanging – they should be on a stool to facilitate hip flexion which increases the interspinous width
    • In the sitting postion the midline is easier to determine and CSF flows are higher, especially in the dehydrated patient. Manometer readings are unreliable however
  • Locating the inter-vertebral space:
    • In adults the spinal cord may terminate as low as the L2 body, therefore LP should performed at the L23, L34, or L5S1 intervertebral spaces.
    • Ask the patient if the needle feels like it is dead centre. People can usually tell if it feels like the needle is off to one side
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About Mike Cadogan

Emergency physician with a passion for medical informatics and medical education. Co-founder of HealthEngine, iMeducate, and the GMEP. He writes more eclectically on the web as @sandnsurf | + Mike Cadogan | Contact