Hypochloraemia (<95) (Usually associated with sodium losses)
Cause of HYPOchloraemia
1) Drugs
- Bicarbonate (Inversely proportional to chloride)
- Steroids
- Diuretics, laxatives (Increased Mg and PO4)
- Theophylline
2) Increased losses (Volume contraction and metabolic alkalosis)
- Excessive sweating
- Excessive diuresis
- Prolonged vomiting (Pyloric stenosis) or NGT aspiration
- Rena – Salt-losing nephropathy
- Adrenocortical deficiency
- Acute intermittent porphyria
- SIADH (Hand in hand with Na)
Associated with metabolic alkalosis in most cases due to sodium retention at expense of hydrogen ions
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