Hypochloraemia

Hypochloraemia (<95) (Usually associated with sodium losses)

Cause of HYPOchloraemia

1)    Drugs

    • Bicarbonate (Inversely proportional to chloride)
    • Steroids
    • Diuretics, laxatives (Increased Mg and PO4)
    • Theophylline

      2)    Increased losses (Volume contraction and metabolic alkalosis)

        • Excessive sweating
        • Excessive diuresis
        • Prolonged vomiting (Pyloric stenosis) or NGT aspiration
        • Rena – Salt-losing nephropathy
          1. Adrenocortical deficiency
          2. Acute intermittent porphyria
          3. SIADH (Hand in hand with Na)

            Associated with metabolic alkalosis in most cases due to sodium retention at expense of hydrogen ions

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            About Mike Cadogan

            Emergency physician with a passion for medical informatics and medical education. I write medical textbooks, websites such as HealthEngine and write more eclectically on the web as @sandnsurf | + Mike Cadogan | Contact