- Sino-atrial exit block is due to failed propagation of pacemaker impulses beyond the SA node.
- The sino-atrial node continues to depolarise normally.
- However, some of the sinus impulses are “blocked” before they can leave the SA node, leading to intermittent failure of atrial depolarisation (dropped P waves).
The SA node consists of two main groups of cells:
- A central core of pacemaking cells (“P cells”) that produce the sinus impulses.
- An outer layer of transitional cells (“T cells”) that transmit the sinus impulses out into the right atrium.
Sinus node dysfunction can result from either:
- Failure of the P cells to produce an impulse. This leads to sinus pauses and sinus arrest.
- Failure of the T cells to transmit the impulse. This leads to sino-atrial exit block.
Patterns of conduction
- The patterns of conduction in SA exit block are identical to the different types of AV block.
- However, as the initial sinus impulse is not visible on the ECG, the relationship between impulse generation and transmission must be inferred from the P waves alone (analogous to examining only the R waves in AV block).
- Only second degree SA block (types I and II) can be diagnosed from the 12-lead ECG.
First Degree SA block
= Delay between impulse generation and transmission to the atrium.
- This abnormality is not detectable on the surface ECG.
Second Degree SA block, Type I (Wenckebach)
= Progressive lengthening of the interval between impulse generation and transmission, culminating in failure of transmission.
- The gradually lengthening transmission interval pushes successive P waves closer together.
- This results in grouping of the P-QRS complexes.
- Pauses due to dropped P waves occur at the end of each group.
- The P-P interval progressively shortens prior to the dropped P wave.
- This pattern is easily mistaken for sinus arrhythmia.
Second Degree SA block, Type II
= Intermittent dropped P waves with a constant interval between impulse generation and atrial depolarisation.
- This pattern is the equivalent of Mobitz II.
- There is no clustering of P-QRS complexes.
- Intermittent P waves “drop out” of the rhythm, while subsequent P waves arrive “on time”.
- The pause surrounding the dropped P wave is an exact multiple of the preceding P-P interval.
Third Degree SA Block
= None of the sinus impulses are conducted to the right atrium.
- There is a complete absence of P waves.
- The onset of 3rd degree SA block may produce long sinus pauses or sinus arrest (may lead to fatal asystole).
- Rhythm may be maintained by a junctional escape rhythm.
- Third degree SA exit block is indistinguishable from sinus arrest due to pacemaker cell failure. It can only be diagnosed with a sinus node electrode during electrophysiological evaluation.
Type I SA block:
- This pattern of grouped beating is characteristic of type I SA block.
- There is progressive shortening of the P-P interval, followed by an absent P wave-QRS complex.
Type II SA block:
- Arrows indicate the presumed timing of each sinus impulse.
- The blue arrows represent normally transmitted impulses, i.e. resulting in P waves.
- The black arrows represent blocked sinus impulses (dropped P waves).
- The pauses around the dropped P waves (2.1 seconds) are exactly double the preceding P-P interval (1.05 seconds)
- The 4th QRS complex is a junctional escape beat followed by a non-conducted P wave (occurring just prior to the T wave).
- The 8th QRS complex is a junctional escape beat. The following P wave is conducted to the ventricles, albeit with an extremely long PR interval (400ms).
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- ECG Reference Sites on the WEB — the best of the rest
- Phibbs BP. Advanced ECG: Boards and Beyond (second edition). Elsevier 2006.
- Saperia GM. Sinoatrial nodal pause; arrest; and exit block [internet article]. Up To Date 2009. Accessible at www.uptodate.com [subscribers only].
- Surawicz B, Knilans T. Chou’s Electrocardiography in Clinical Practice (6th edition), Saunders 2008.
- Ufberg JW. Sinoatrial exit block [chapter]. In: TC Chan, WJ Brady, RA Harrigan, JP Ornato and PR Rosen (editors). ECG in Emergency Medicine and Acute Care. Elsevier 2005. Chapter 19, pp83-85.