Clinical Toxicologist Nicholas Buckley is one of the biggest brains in the business. In his talk at SMACC he showed us how much there is to know about something so seemingly simple in ‘Paracetamol: More than meets the Eye’. This is a really great talk — enjoy!
Listen to the audio by clicking here and view the slides:
Buckley’s analysis of liver transplantation in paracetamol hepatotoxicity particularly fascinates me, to the extent that I wrote a detailed CCC entry on Liver Transplantation for Paracetamol Toxicity. and presented it as part of my talk on ‘Toxicological Myths and Half-Truths’ at the CICM ASM in Wellington this year.
Other useful LITFL links include:
- CCC — Acute Paracetamol Toxicity
- Toxicology Conundrum 001 — Paracetamol… Too much, too often?
- Toxicology Conundrum 051 — Paracetamol-induced hepatotoxicity
Oh, and be sure you know the Australasian guidelines, Buckley’s talk goes well beyond this:
- Daly FF, Fountain JS, Murray L, Graudins A, Buckley NA; Panel of Australian and New Zealand clinical toxicologists. Guidelines for the management of paracetamol poisoning in Australia and New Zealand–explanation and elaboration. A consensus statement from clinical toxicologists consulting to the Australasian poisons information centres. Med J Aust. 2008 Mar 3;188(5):296-301 [full text]