An essential co-factor in the synthesis of clotting factors II, VII, IX and X. It is used for the reversal of coumadin-induced coagulopathy.
References
- Bruno GR, Howland MA, McMeeding et al. Long-acting anticoagulant overdose: brodifacoum kinetics and optimal vitamin K dosing. Annals of Emergency Medicine 2000; 36(3):262-267.
- Isbister GK, Hackett LP and Whyte IM. Intentional warfarin overdose. Therapeutic Drug Monitoring 2003; 25(6):715-722.
- Baker RI, Coughlin PB, Gallus AS et al. Warfarin reversal: consensus guidelines, on behalf of the Australasian Society of Thrombosis and Haemostasis. Medical Journal of Australia 2004; 181(9):492-497.
- Dentali F, Ageno W, Crowther M. Treatment of coumarin-associated coagulopathy: a systematic review and proposed treatment algorithms. Journal of Thrombosis and Haemostasis 2006; 4:1853-1863.
About Mike Cadogan
[...] Vitamin K [...]