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Tramadol

Tramadol is a centrally-acting synthetic analgesic. In overdose, it frequently causes delayed-onset seizures. It may also cause mild sedation and respiratory depression

References

  • Persson H, Sjöberg G. Acute toxicity of tramadol – analyses of 287 cases (abstract). Clinical
  • Toxicology 2008; 46:398.
  • Sachdeva DK, Stadnyk JM. Are one or two dangerous? Opioid exposure in toddlers. The Journal of Emergency Medicine 2005; 29(1):77-84.
  • Shadnia S, Soltaninejad K, Heyardi K et al. Tramadol intoxication: a review of 114 cases. Human and Experimental Toxicology 2008; 27:201-205.
  • Spiller HA, Gorman SE, Villalobos D et al. Prospective multicenter evaluation of tramadol exposure. Journal of Toxicology-Clinical Toxicology 1997; 35(4):361-364.

Toxicology Handbook

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About Mike Cadogan

Emergency physician with a passion for medical informatics and medical education. Co-founder of HealthEngine, iMeducate, and the GMEP. He writes more eclectically on the web as @sandnsurf | + Mike Cadogan | Contact