Thyroxine

Overdose of thyroxine is rarely sufficient to produce significant symptoms of hyperthyroidism. When these do occur, they are mild, delayed in onset and may last up to two weeks. They can usually be successfully managed in the outpatient setting.

References

• Lewander WJ, Lacouture PG, Silva JE et al. Acute thyroxine ingestion in pediatric patients. Pediatrics 1989; 84:262-265.
• Litovitz TL, White JD. Levothyroxine ingestions in children: An analysis of 78 cases. American Journal of Emergency Medicine 1985; 3:297-300.
• Shilo L, Kovatz S, Hadari R et al.  Massive thyroid hormone overdose: Clinical manifestations and management.  Israeli Medical Association Journal 2002; 4:298-289.
• Tunget CL, Clark RF, Turchen SG et al. Raising the decontamination level for thyroid hormone ingestions. American Journal of Emergency Medicine 1995; 13:9-13.