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Theophylline

Theophylline has an extremely narrow therapeutic index and both acute overdose and chronic toxicity are potentially life-threatening. Aggressive supportive care and early accurate risk assessment to determine the need for dialysis ensure a favourable outcome

References

  • Minton NA and Henry JA. Treatment of theophylline overdose.  American Journal of Emergency Medicine 1996;14:606-612.
  • Shannon M.  Life-threatening events after theophylline overdose: a 10-year prospective analysis.  Archives of Internal Medicine 1999;159:989-994.

Toxicology Handbook

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About Mike Cadogan

Emergency physician with a passion for medical informatics and medical education. Co-founder of HealthEngine, iMeducate, and the GMEP. He writes more eclectically on the web as @sandnsurf | + Mike Cadogan | Contact