Sodium Thiosulfate enhances the endogenous cyanide detoxification capacity of the body. It is suitable to use alone in the treatment of mild to moderately severe cases of cyanide poisoning but should be used in conjunction with other antidotes in severe cyanide toxicity.
References
- Hall AH, Dart R, Bogdan G. Sodium thiosulfate or hydroxycobalamin for empiric treatment of cyanide poisoning? Annals of Emergency Medicine 2007; 49:806-813.
- IPCS/CEC evaluation of antidotes series. Volume 2. Antidotes for poisoning by cyanide. Meredith TJ, Jacobsen D, Haines JA and Berger J-C. Cambridge University Press 1993.
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