Quinine

Quinine toxicity is characterised by “cinchonism” consisting of nausea, vomiting, tinnitus vertigo and deafness. Larger overdoses may result in life-threatening cardiotoxicity and severe, potentially permanent, visual disturbance.

References

  • Langford NJ, Good AM, Laing WJ et al. Quinine intoxications reported to the Scottish Poisons Information Bureau 1997–2002: A continuing problem. British Journal of Clinical Pharmacology 2003; 56:576–578.
  • Guly U, Driscoll P. The management of quinine-induced blindness. Archives of Emergency Medicine 1992; 9:317-322.
  • Boland ME, Roper SM, Henry JA. Complications of Quinine Poisoning.  The Lancet 1985; 1(8425):384-385.

Huston M, Levinson M. Are one or two dangerous? Quinine and quinidine exposure in toddlers. The Journal of Emergency Medicine 2006; 31(4):395–401.

Toxicology Handbook

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About Mike Cadogan

Emergency physician with a passion for medical informatics and medical education. Co-founder of HealthEngine, iMeducate, and the GMEP. He writes more eclectically on the web as @sandnsurf | + Mike Cadogan | Contact