Pralidoxime

This is the oxime commonly used in Australia to reactivate acetylcholinesterase inhibition caused by organophosphates (OPs).

References

  • Buckley NA. Eddleston M. Szinicz L. Oximes for acute organophosphate pesticide poisoning. Cochrane Database of Systematic Reviews 2005(1):CD005085.
  • Eddleston M, Eyer P, Worek F et al.  Pralidoxime in acute organophosphorus insecticide poisoning – a randomised controlled trial.  PLoS Med. 2009 June; 6(6):e1000104. Published online 2009 June 30.

Toxicology Handbook

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About Mike Cadogan

Emergency physician with a passion for medical informatics and medical education. Co-founder of HealthEngine, iMeducate, and the GMEP. He writes more eclectically on the web as @sandnsurf | + Mike Cadogan | Contact