Opioid intoxication causes CNS and respiratory depression. Death is due to respiratory failure. Good supportive care ensures survival. The specific antidote, naloxone, can assist the management of airway and breathing. Some opioids possess unexpected toxic effects (e.g. dextropropoxyphene).
References
- Sachdeva DK, Stadnyk JM. Are one or two dangerous? Opioid exposure in toddlers. The Journal of Emergency Medicine 2005; 29(1): 77-84
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