Overdose with any of the NSAIDs, unless the ingestion is massive, is benign. Management is symptomatic and supportive. Ibuprofen accounts for over two thirds of NSAID deliberate self-poisoning cases.
References
- Balali-Mood M, Critchley JA, Proudfoot AT et al. Mefenamic acid overdose. Lancet 1981: 1;1354-1356.
- Hall AH, Smolinske SC, Stover B et al. Ibuprofen overdose in adults. Journal of Toxicology-Clinical Toxicology 1992; 30(1):23-27.
- Hall AH, Smolinske SC, Conrad FL et al. Ibuprofen overdose: 126 cases. Annals of Emergency Medicine 1986; 15:1308-1313.
- McElwee NE, Veltri JC, Bradford DC et al. A prospective, population-based study of acute ibuprofen overdose: Complications are rare and routine serum levels not warranted. Annals of Emergency Medicine 1990; 19(6):657-652.
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