Neuroleptic malignant syndrome (NMS) is a rare but potentially lethal syndrome complicating the use of neuroleptic medications. It is characterised by neuromuscular rigidity, altered mental status and autonomic instability.
References
- Bhanushali MJ, Tuite PJ. The evaluation and management of patients with neuroleptic malignant syndrome. Neurology Clinics of North America 2004; 22: 389-411.
- Neuroleptic malignant syndrome. In: Diagnostic and statistical manual of mental disorders, 4th edition. Washington DC. American Psychiatric Association 1994: 739-742.
- Rusyniak DE, Sprague JE. Toxin-induced hyperthermic syndromes. Medical Clinics of North America 2005; 89:1277-1296.
- Trollor JN, Chen X, Sachdev PS. Neuroleptic malignant syndrome associated with atypical antipsychotic drugs. CNS drugs 2009; 23(6):477-492.
About Mike Cadogan
