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Local Anaesthetic Agents

Local anaesthetic (LA) toxicity is nearly always the result of a therapeutic error. It occurs because of incorrect dose, route of administration or technique. Care for this potentially life-threatening toxicity is primarily supportive although use of intralipid may play an important role in severe cases.

References

  • Felice KL, Schumann HM.  Intravenous lipid emulsion for local anesthetic toxicity: a review of the literature.  Journal of Medical Toxicology 2008; 4(3):184-191.
  • Weinberg G.  Lipid rescue resuscitation from local anaesthetic cardiac toxicity.  Toxicological Reviews 2006; 25(3):139-145.

Toxicology Handbook

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About Mike Cadogan

Emergency physician with a passion for medical informatics and medical education. Co-founder of HealthEngine, iMeducate, and the GMEP. He writes more eclectically on the web as @sandnsurf | + Mike Cadogan | Contact