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Isoniazid

Isoniazid overdose is rare but potentially fatal. Severe poisoning presents with rapid onset of seizures, coma and severe metabolic acidosis. Pyridoxine is the specific antidote.

References

  • Alvarez FG, Guntupalli KK. Isoniazid overdose: four case reports and review of the literature. Intesive Care Medicien 1995; 21(8):641-644..

Toxicology Handbook

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About Mike Cadogan

Emergency physician with a passion for medical informatics and medical education. Co-founder of HealthEngine, iMeducate, and the GMEP. He writes more eclectically on the web as @sandnsurf | + Mike Cadogan | Contact