Diphenoxylate-atropine

This combination drug causes delayed onset of opioid and anticholinergic effects when ingested by children, even in small amounts.

References

  • McCarron MM, Chalhower KR, Thompson GA.  Dipheoxylate-atropine (Lomotil) overdose in children: an update (report of 8 cases and review of the literature).  Pediatrics 1991; 87(5):694-700.
  • Thomas TJ, Pauze D, Love JN. Are one or two dangerous? – Diphenoxylate-atropine exposure in toddlers. The Journal of Emergency Medicine 2008; 34(1):71-75.

Toxicology Handbook

Print Friendly
About Mike Cadogan

Emergency physician with a passion for medical informatics and medical education. Founder of GMEP and HealthEngine. Asynchronous learning and #FOAMed evangelist | @sandnsurf | + Mike Cadogan | Contact