Colchicine overdose is uncommon but potentially lethal. Toxicity is characterised by severe gastroenteritis followed by multi-organ failure. Aggressive decontamination and supportive care are the cornerstones of management.
References
- Harris R, Gillet M. Colchicine poisoning – overview and new directions. Emergency Medicine 1998; 10; 161-167.
- Jayaprakash V, Ansell G, Galler D. Colchicine overdose: the devil is in the detail. The New Zealand Medical Journal 2007; 120(1248):81-88.
About Mike Cadogan
