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Anticoagulant rodenticides

Long-acting anticoagulant rodenticides or “superwarfarins” were developed to counter rodent resistance to warfarin. Single unintentional paediatric ingestions are non-toxic. In contrast, massive or repeated dosing leads to profound and prolonged (weeks-months) anticoagulation.

References

  • Ingels M. Lai C, Tai, W et al. A prospective study of acute, unintentional, pediatric superwarfarin ingestions managed without decontamination .  Annals of Emergency Medicine 2002; 40(1):73-78.
  • Shepherd G. Klein-Schwartz W, Anderson BD.  Acute unintentional pediatric brodifacoum ingestions. Pediatric Emergency Care 2002; 18(3):174-178.
  • Watt BE, Proudfoot AT, Bradberry SM et al. Anticoagulant rodenticides. Toxicological Reviews 2005; 24(4): 259-269.

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About Mike Cadogan

Emergency physician with a passion for medical informatics and medical education. Co-founder of HealthEngine, iMeducate, and the GMEP. He writes more eclectically on the web as @sandnsurf | + Mike Cadogan | Contact