R&R in the FASTLANE 008

The eighth edition of our weekly series of eminence-based evidence:

R&R in the FASTLANE 008 RR IN THE FASTLANE LOGO 21 590x213

A free weekly resource that harnesses the power of social media to allow some of the best and brightest emergency medicine and critical care clinicians from all over the world tell us what they think is worth reading from the published literature.

This edition contains 14 recommended reads. Find out more about the R&R in the FASTLANE project here and check out the team of contributors from all around the world.

This week’s ‘R&R Hall of Famers’

  • Abd-el-Maeboud KH, el-Naggar T, el-Hawi EM, Mahmoud SA, Abd-el-Hay S. Rectal suppository: commonsense and mode of insertion. Lancet. 1991 Sep 28;338(8770):798-800. PMID: 1681170

R&R in the FASTLANE 008 RR WTF 64 R&R in the FASTLANE 008 RR Hall of fame 64

This little known classic has never been repeated, but it has sparked a debate that continues to this day: What is the best direction to place a suppository – pointy or blunt end first? The authors challenged conventional wisdom as well as manufacturer instructions and tested their theory – that blunt end was best – on 100 unwitting patients. The rate of needing to insert a digit in the anal canal to push the suppository further in was 1% in the blunt end group versus 83% for pointy end first. Unwanted suppository expulsion rate was also lower in the blunt end group.  Since this is the only study of its kind, questions have been raised as to whether it should be practice changing. It is for me. That’s all I can say.

Recommended by Rob Orman
Learn more: ERCAST – The Suppository Conundrum

  • Hudson ML, Moore GP. Defenses to Malpractice: What Every Emergency Physician Should Know. J Emerg Med 2011;41:598-606. PMID: 21094012

R&R in the FASTLANE 008 RR GameChanger 64 R&R in the FASTLANE 008 RR Hall of fame 64

A medical malpractice suit must contain four elements: duty; breach of standard of care (negligence); injury; and proximate cause. However, even if all these factors exists, there are additional specific defenses that physician can claim: including contributory negligence, comparative fault, respectable minority, clinical innovation, and Good Samaritan exclusion. Although most of these specific defenses seem to me included in the original 4 elements, the authors give a good summary of this topic.

Recommended by Leon Gussow

This week’s R&R recommendations

  • Kumar RD, Hirsch NP. Clinical evaluation of stethoscope-guided inflation of tracheal tube cuffs. Anaesthesia. 2011 Nov;66(11):1012-6. doi: 10.1111/j.1365-2044.2011.06853.x. Epub 2011 Aug 18. PMID: 21851343.
R&R in the FASTLANE 008 RR Eureka 64 A cool, practical study although patient numbers are small.

Recommended by Sa’ad Lahri

  • Bershad EM, Suarez JI. Prothrombin complex concentrates for oral anticoagulant therapy-related intracranial hemorrhage: a review of the literature. Neurocrit Care. 2010 Jun;12(3):403-13. Review. PMID: 19967567.

R&R in the FASTLANE 008 RR GameChanger 64

PCC Review:  PCCs ARE AVAILABLE IN THE US!!!  PRofilNine SD is roughly equivalent to Octaplex!

Recommended by Mike Jasumback

  • Latronico N, Bolton CF. Critical illness polyneuropathy and myopathy: a major cause of muscle weakness and paralysis. Lancet Neurol. 2011 Oct;10(10):931-41. Review. PMID: 21939902.

R&R in the FASTLANE 008 RR GameChanger 64

Go the early rehab. A good review of a classic topic.

Recommended by Oliver Flower

  • Armfield DR, Kim DH, Towers JD, Bradley JP, Robertson DD. Sports-related muscle injury in the lower extremity. Clin Sports Med. 2006 Oct;25(4):803-42. PMID: 16962427

R&R in the FASTLANE 008 RR Mona Lisa 64

We see lots of muscle strains and soft tissue injurys. This is a good review of what specific anatomic injuries are occurring.

Recommended by Andy Neill

  • Hudson ML, Moore GP. Defenses to Malpractice: What Every Emergency Physician Should Know. J Emerg Med 2011;41:598-606. PMID: 21094012

R&R in the FASTLANE 008 RR GameChanger 64 R&R in the FASTLANE 008 RR Hall of fame 64

A medical malpractice suit must contain four elements: duty; breach of standard of care (negligence); injury; and proximate cause. However, even if all these factors exists, there are additional specific defenses that physician can claim: including contributory negligence, comparative fault, respectable minority, clinical innovation, and Good Samaritan exclusion. Although most of these specific defenses seem to me included in the original 4 elements, the authors give a good summary of this topic.

Recommended by Leon Gussow

  • Nguyen-Khac E, Thevenot T, Piquet MA, Benferhat S, Goria O, Chatelain D, Tramier B, Dewaele F, Ghrib S, Rudler M, Carbonell N, Tossou H, Bental A, Bernard-Chabert B, Dupas JL; AAH-NAC Study Group. Glucocorticoids plus N-acetylcysteine in severe alcoholic hepatitis. N Engl J Med. 2011 Nov 10;365(19):1781-9. PMID: 22070475.

R&R in the FASTLANE 008 RR GameChanger 64

NAC – is there anything we can’t try it for. Negative trial statistically but results all leaning toward benefit. 8% v 24% mortality at 1 month vs placebo

Recommended by Andy Neill
Learn more: Emergency Medicine Ireland – NAC for alcoholic hepatitis

  • Vazirani J, Knott JC. Mandatory Pain Scoring at Triage Reduces Time to Analgesia. Ann Emerg Med. 2011 Sep 9. PMID: 21908072

R&R in the FASTLANE 008 RR GameChanger 64

If you want your patients to get analgesia quicker… ask the triage nurse to do analgesia scores. Will it affect the ATS category as well??

Recommended by Ioana Vlad

  • Mellick LB. Torsion of the Testicle: It Is Time to Stop Tossing the Dice. Pediatr Emer Care 2012;28:80-86. PMID: 22217895

R&R in the FASTLANE 008 RR Eureka 64

Great in-depth discussion of the myths and misconceptions related to the presentation and diagnosis of testicular torsion. Bottom line recommendation: image every patient with scrotal or testicular pain whose history and physical is not consistent with torsion. Clinically obvious torsion should go directly to urology for exploration.

Recommended by Leon Gussow

  • Abd-el-Maeboud KH, el-Naggar T, el-Hawi EM, Mahmoud SA, Abd-el-Hay S. Rectal suppository: commonsense and mode of insertion. Lancet. 1991 Sep 28;338(8770):798-800. PMID: 1681170

R&R in the FASTLANE 008 RR WTF 64 R&R in the FASTLANE 008 RR Hall of fame 64

This little known classic has never been repeated, but it has sparked a debate that continues to this day: What is the best direction to place a suppository – pointy or blunt end first? The authors challenged conventional wisdom as well as manufacturer instructions and tested their theory – that blunt end was best – on 100 unwitting patients. The rate of needing to insert a digit in the anal canal to push the suppository further in was 1% in the blunt end group versus 83% for pointy end first. Unwanted suppository expulsion rate was also lower in the blunt end group.  Since this is the only study of its kind, questions have been raised as to whether it should be practice changing. It is for me. That’s all I can say.

Recommended by Rob Orman
Learn more: ERCAST – The Suppository Conundrum

  • Doyal L. Should the skeleton of “the Irish giant” be buried at sea?. BMJ 2011; 343. PMID: 22187392

R&R in the FASTLANE 008 RR WTF 64

A story from a time when ethics was not a word.

Recommended by Ioana Vlad

  • Weber JM et al. Can Nebulized Naloxone Be Used Safely and Effectively by Emergency Medical Services for Suspected Opioid Overdose? Prehosp Emerg Care 2011 Dec 22. [Epub ahead of print] PMID: 22191727

R&R in the FASTLANE 008 RR Eureka 64

Nebulized naloxone appears to be a safe and effective option for prehospital treatment of the non-emergent patient with suspected opiate toxicity.

Recommended by Leon Gussow

  • Nielsen AS, Damek DM. Window of opportunity: Flexion myelopathy after drug overdose. J Emerg Med. 2008 Dec 10. PMID: 19081699

R&R in the FASTLANE 008 RR WTF 64

One question you probably haven’t thought to ask the paramedics!

Recommended by Ioana Vlad

  • James MF, Michell WL, Joubert IA, Nicol AJ, Navsaria PH, Gillespie RS. James MF, Michell WL, Joubert IA, Nicol AJ, Navsaria PH, Gillespie RS. Resuscitation with hydroxyethyl starch improves renal function and  lactate clearance in penetrating trauma in a randomized controlled study: the FIRST trial (Fluids in Resuscitation of Severe Trauma). Br J Anaesth. 2011 Nov;107(5):693-702. PMID: 21857015
R&R in the FASTLANE 008 RR Hot Stuff 64 This is the first randomized, controlled, double-blind study comparing crystalloids with isotonic colloids in trauma.

Recommended by Cliff Reid
Learn more: Resus.ME – FIRST: Fluid Resuscitation in Severe Trauma

  • Rosenberg H, Rosenberg H, Hickey M. Emergency management of a traumatic tooth avulsion. Ann Emerg Med. 2011 Apr;57(4):375-7. PMID: 20817349

R&R in the FASTLANE 008 RR Eureka 64

Got an avulsed tooth at 3 am, but no dentist/ oral surgeon on call? How do you temporarily stabilize the tooth once reimplanted? Dermabond + nasal bridge of N95 mask = stabilized tooth!

Recommended by Michelle Lin
Learn more: Academic Life in Emergency Medicine – Trick of the Trade: Dental Injury

The R&R iconoclastic sneak peek icon key

R&R in the FASTLANE 008 RR Authors 64 The list of contributorsR&R in the FASTLANE 008 RR Vault 64 The R&R ARCHIVE
R&R in the FASTLANE 008 RR Hall of fame 64 R&R Hall of fame
You simply MUST READ this!
R&R in the FASTLANE 008 RR Hot Stuff 64 R&R Hot stuff!
Everyone ‘s going to be talking about this
R&R in the FASTLANE 008 RR Landmark 64 R&R Landmark paper
A paper that made a difference
R&R in the FASTLANE 008 RR GameChanger 64 R&R Game Changer?
Might change your clinical practice
R&R in the FASTLANE 008 RR Eureka 64 R&R Eureka!
Revolutionary idea or concept
R&R in the FASTLANE 008 RR WTF 64 R&R WTF!
Weird, transcendent or funtabulous!
R&R in the FASTLANE 008 RR Boffin 64 R&R Boffintastic
High quality research
R&R in the FASTLANE 008 RR Trash 64 R&R Trash
Must read, because it is so wrong!
R&R in the FASTLANE 008 RR Mona Lisa 64 R&R Mona Lisa
Brilliant writing or explanation

That’s it for now…

That should keep you busy for a week at least… Leave a comment below if you have any queries, suggestions, or comments about this week’s R&R in the FASTLANE or if you want to tell us what you think is worth reading.

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About Chris Nickson

An oslerphile suffering from a bad case of knowledge dipsosis. Key areas of interest include: emergency medicine, critical care, toxicology, tropical medicine, clinical epidemiology, history, literature and the internet-learning revolution. @precordialthump | + Chris Nickson | Contact

Comments

  1. Duncan says:

    “NAC – is there anything we can’t try it for.”

    It’s not a novel ED treatment until it’s held its own against IV Mg++ and bedside USS.

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