The Antidote Challenge

aka Toxicology Conundrum 031

OK.
You’ve survived the Australian elapid snakebite envenoming challenge, took the toxidrome challenge in your stride, and simply brushed aside the ‘sniff a poison’ challenge.
What’s next?…
The antidote challenge.

How this works

For each of the poisons listed below see if you can name the appropriate antidote(s), click on the link to show/hide the answer.

What are you going to reach for in the antidote locker? (Photo by Hey Skinny)

The Antidote Challenge

Amanita mushrooms (amatoxin) — Show answer
silibinin, penicillin
amitriptyline — Show answer
sodium bicarbonate
(see Toxicology Conundrum 022)
arsenic — Show answer
dimercaprol/ BAL (British Antilewisite)
beta blockers — Show answer
glucagon, high-dose insulin euglycaemic therapy (HIET)
benzodiazepines — Show answer
flumazenil
bupivacaine — Show answer
sodium bicarbonate, intralipid
cesium — Show answer
prussian blue (actually not an antidote, but a specific agent used for gastrointestinal decontamination and enhanced elimination)
citalopram — Show answer
cyproheptadine, benzodiazepines for serotonin toxicity
(see Toxicology Conundrums 017 and 024)
copper — Show answer
penicillamine
cyanide — Show answer
thiosulfate, hydrocobalamin (also – dicobalt edetate)
digoxin — Show answer
digoxin specific immune Fab fragments
glipizide — Show answer
glucose, octreotide
heparin — Show answer
protamine
hydrofluoric acid — Show answer
calcium
hyoscine — Show answer
physostigmine
iron — Show answer
desferrioxamine
isoniazid — Show answer
pyridoxine
magnesium — Show answer
calcium
methanol, ethylene glycol — Show answer
ethanol, fomepizole (4-methylpyrazole)
methemoglobinemia — Show answer
methylene blue
methotrexate — Show answer
folinic acid
mercury (inorganic salt) — Show answer
dimercaprol (aka British Antilewisite, BAL)
Oleander poisoning — Show answer
digoxin specific immune Fab fragments
organophosphate — Show answer
atropine, pralidoxime
opiates — Show answer
naloxone
(see Toxicology Conundrum 006)
lead — Show answer
dimercaprol (aka British Antilewisite, BAL) and EDTA, or succimer (DMSA) if mild or asymptomatic with high levels
paracetamol — Show answer
n-acetylcysteine
(see Toxicology Conundrum 001)
thallium — Show answer
prussian blue (actually not an antidote, but a specific agent used for gastrointestinal decontamination and enhanced elimination)
verapamil — Show answer
calcium, high-dose insulin euglycaemic therapy
(see Toxicology Conundrum 028)
warfarin — Show answer
vitamin K
(see Toxicology Conundrums 015, 016 and 021)