September 2, 2010

AAA rupture and rhabdomyolysis

Renal Riddle 001

Consider a 65 year-old male presenting with right-sided flank pain radiating to the groin.  The following CT scan was taken to confirm a presumed diagnosis of renal colic:

image 114 AAA rupture and rhabdomyolysis

image 210 AAA rupture and rhabdomyolysis

Questions

Q1.  Describe the CT scan

CT scan is non-contrast; however, there is:

  • right-sided retroperitoneal blood evident
  • an abdominal aortic aneurysm

It is important to remember that the commonest cause of the ‘classic’ presentation of renal colic amongst patients presenting to have a post-mortem is ruptured abdominal aortic aneurysm.

This patient needs an emergency AAA repair.

The patient was taken to theatre for emergency surgery.
The following biochemistry results were taken post-operatively:

image 37 AAA rupture and rhabdomyolysis

Q2.  Describe the biochemistry.  What diagnosis is suggested by these biochemical findings?

Biochemistry demonstrates acute renal failure with a reduced urea-to-creatinine ratio.

The likely diagnosis is rhabomyolysis in this clinical context.

Features suggestive of this diagnosis are:

  • increased urea and creatinine with a reduced urea-to-creatinine ratio
  • hyperphosphataemia, hypocalcaemia, hyperkalaemia
  • metabolic acidosis
  • increased CK (usually to greater than 40,000)
  • Although not measured here, AST, and LDH are also increased in rhabdomyolysis

Q3.  What are the other potential causes of renal failure to consider in this clinical situation?

Other potential causes:

  1. hypovolaemia from bleeding
  2. renal artery occlusion during operation
  3. use of contrast in pre-operative CT scan (not in this case)
  4. use of nephrotoxic drugs like gentamicin
  5. low cardiac output from peri-operative myocardial infarction
  6. abdominal compartment syndrome

Related Posts

  1. Unusual Urine 004
  2. Patellar Tendon Rupture
  3. Intra-aortic Balloon Pump Trouble-shooting
  4. Quiz Lab Tests 003
  5. Hemolysis and renal failure in a toddler

About Paul Young
A proud graduate of The Breakfast Club, Paul is an Intensivist in Wellington, New Zealand. According to his father, Paul studied medicine after performing a cost-effectiveness analysis of his own biomedical fragility – a champion runner as a youth, he now struggles with a zimmer frame. Although he started out in the ED, Paul feels physically ill whenever he steps foot there these days.

Comments

  1. 'In the Fast Lane': Renal Riddle #001 http://su.pr/18dVk7 It's not a problem with the kidney… or is it?

  2. Joel Topf says:

    AAA presenting as renal colic. I have not seen that. Cool.

    http://lifeinthefastlane.com/2009/12/renal-riddle-001/

  3. Paras says:

    RT @kidney_boy: AAA presenting as renal colic. I have not seen that. Cool.

    http://lifeinthefastlane.com/2009/12/renal-riddle-001/

Trackbacks

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