Question
a. How would you distinguish between neuroleptic malignant syndrome and serotonin syndrome? (50%) b. Outline your management of neuroleptic malignant syndrome. (25%) c. Outline your management of serotonin syndrome. (25%)
Answer
FACEM SAQ Exam 2005.2 – Question 2
- The overall pass rate for this question was 28/56 (50%).
- Pass Criteria
- It was expected that answers would make clear the causative agents, time course and classic clinical features of both syndromes.
- Better answers made clear both the useful differentiating points and the common features.
- The management questions were expected to include both general supportive measures such as IV fluids, cooling and prevention of muscle breakdown induced renal impairment, as well as syndrome specific drug treatments.
- Features of unsuccessful answers
- Failing management answers drew little distinction between the two syndromes and were light on with respect to specific therapies such as bromocriptine, cyproheptadine and chlorpromazine.

















